5-Amino IMQ (Cloruro)

SKU: 5AMINO1MQ-50

Disponible

$50.00

MG:

50 mg

Variante

5-Amino-IMQ (cloruro) es un derivado sintético de imidazoquinolina de molécula pequeña suministrado como sal de cloruro y estructuralmente relacionado con los compuestos basados en imiquimod. Caracterizado por su identidad química definida, bajo peso molecular y estructura aromática heterocíclica, el 5-Amino-IMQ es ampliamente referenciado en la literatura científica como un compuesto de investigación utilizado en estudios de señalización inmunitaria innata e interacción receptor-ligando, particularmente en investigaciones que involucran la activación de la vía del receptor tipo Toll (TLR) a nivel molecular. Con propiedades fisicoquímicas documentadas y síntesis reproducible.

Product Specifications

Size: 50 mg
Form: Lyophilized Powder
Appearance:
Weight: 0.2 lb
Dimensions: 2" x 2" x 2"

COA's & Testing

Chemical Purity: >99%
Purity & Identification Testing: HPLC & Mass Spectrometry
Net Content Weight Testing: Milligram Weight
Endotoxin Testing: < 0% Bacterial Endotoxins

Regulatory & Intended Use

Regulatory Status: Solo para uso en investigación (RUO)
Chemical Grade: Laboratory, Research y Analytical

Research-Use Attestation

I confirm I am 21+ years of age or older.

I certify the information provided is true and accurate. I confirm this purchase is for laboratory research use only (not for human or animal consumption). I acknowledge the company may use IP address and other reasonable verification methods to authenticate the information provided.

Scientific Background

Discovery and Development
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to obesity, insulin resistance, and metabolic dysfunction. NNMT emerged as a therapeutic target in the early 2010s. Researchers at the University of Texas Medical Branch, led by Stanley Watowich and Harshini Neelakantan, developed and validated 5-Amino-1MQ as a potent, cell-permeable NNMT inhibitor. The compound was identified through structure-activity studies and shown to increase NAD+ levels, reduce 1-methylnicotinamide production, and improve metabolic parameters in preclinical models.

Key Milestones in Research

Early 2010s: NNMT identified as a promising target for obesity and metabolic disease research.
2017: Publication of key study demonstrating that 5-Amino-1MQ reverses diet-induced obesity, reduces adipose tissue mass, and improves metabolic markers in mice.
2018–Present: Continued preclinical research exploring NNMT inhibition for obesity, type 2 diabetes, fatty liver disease, and related metabolic conditions.

5-Amino-1MQ remains a valuable research tool for investigators studying NNMT biology, NAD+ metabolism, and small-molecule approaches to metabolic regulation.

Why researchers choose Ceritide Research 5-Amino-1MQ: High-purity small-molecule NNMT inhibitor suitable for metabolic, mitochondrial, and obesity-related pathway research.

5-Amino IMQ (Chloride)

CAS:
Molecular Formula:
Molecular Weight:
Amino Length: 0 Aminoácidos
Classification:
Structure:
Sequence:
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NIH PubChem:
NIH PubMed Article:

Storage Guidelines

Peptide Storage Guidelines: Best Practices for Research Stability

At Ceritide Research, we provide high-purity peptides for laboratory and scientific research. Proper storage preserves peptide integrity and supports reliable experimental results.

Storage Guidelines for Lyophilized (Powder) Peptides

Long-Term Storage: Keep at -20°C (-4°F) or lower (ideally -80°C / -112°F) for multi-year stability.
Short-Term Storage: Refrigerate at 2–8°C (36–46°F) for weeks to a few months. Minimize room temperature exposure.
Best Practices: Store in airtight vials with desiccants. Allow vials to reach room temperature in a desiccator before opening. Protect from light and moisture. Aliquot to reduce freeze-thaw cycles.

Storage Guidelines for Reconstituted Peptide Solutions

Once dissolved, peptides are less stable and should be used promptly:

Recommended Temperature: Store at 2–8°C (36–46°F) (refrigerator) for short-term use, typically up to 1–4 weeks depending on the sequence and buffer.
Longer-Term Solution Storage: Aliquot and freeze at -20°C (-4°F) or lower. Avoid storing solutions long-term when possible.
Best Practices: Use sterile techniques, bacteriostatic water or research-grade buffers, and minimize exposure to air and light. Prevent repeated freeze-thaw cycles.

For Research Use Only
All products from Ceritide Research are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Our peptides are intended exclusively for in vitro scientific research and are not for human or veterinary use.

5-Amino IMQ (Cloruro)

$50.00

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Pureza 99%+

Todos los productos se venden únicamente para fines de investigación, laboratorio o análisis, y no son aptos para el consumo humano.