KLOW - GHK-Cu + BPC-157 + TB-500 + KPV

SKU: KLOW-80

$120.00

Disponible

MG:

50/10/10/10MG

Variante

KLOW es una mezcla de investigación de multipéptidos sintéticos que comprende cuatro péptidos bien caracterizados en un total de 80 mg de polvo liofilizado, formulado para investigaciones de laboratorio y analíticas. La mezcla contiene BPC-157 (10 mg), un péptido sintético de 15 aminoácidos derivado de una secuencia identificada en la proteína del jugo gástrico humano; TB-500 (10 mg), un fragmento de 43 aminoácidos de la proteína de origen natural timosina beta-4; GHK-Cu (50 mg), un tripéptido unido a cobre aislado por primera vez del plasma sanguíneo humano en 1973; y KPV (10 mg), un fragmento de tres aminoácidos de la región C-terminal de la hormona estimulante de melanocitos alfa. El polvo aparece de blanco a blanquecino con un ligero tinte azul atribuible al complejo de cobre en GHK-Cu, cada componente posee una identidad química establecida y una estructura molecular documentada.

Product Specifications

Size: 80 mg
Form: Lyophilized Powder
Color: Clear y Blue
Appearance: Blue powder
Weight: 0.2 lb
Dimensions: 2" x 2" x 2"

COA's & Testing

Chemical Purity: >99%
Purity & Identification Testing: HPLC & Mass Spectrometry
Net Content Weight Testing: Milligram Weight
Endotoxin Testing: < 0% Bacterial Endotoxins

Regulatory & Intended Use

Regulatory Status: Solo para uso en investigación (RUO)
Chemical Grade: Laboratory, Research y Analytical

Research-Use Attestation

I confirm I am 21+ years of age or older.

I certify the information provided is true and accurate. I confirm this purchase is for laboratory research use only (not for human or animal consumption). I acknowledge the company may use IP address and other reasonable verification methods to authenticate the information provided.

Scientific Background

Discovery and Development
Klow Blend is a modern synergistic research formulation that combines four established peptides: GHK-Cu (discovered by Loren Pickart in 1973), BPC-157 (isolated in 1993 by Predrag Sikiric’s team), TB-500/Thymosin Beta-4 (discovered in 1981), and KPV (the C-terminal tripeptide fragment of α-MSH). The specific 50mg/10mg/10mg/10mg combination emerged in recent years as researchers explored multi-peptide synergies for regenerative, anti-inflammatory, and skin-focused applications. It represents a compounded approach rather than a single newly discovered molecule.

Key Milestones in Research

1973–1993: Foundational discoveries of the individual components (GHK-Cu, TB4, BPC-157, and KPV as an α-MSH fragment).
2010s–2020s: Growing interest in blended peptide formulations for studying combined effects on tissue repair, inflammation modulation, and skin health.
Present: Continued laboratory use of multi-peptide blends like Klow to investigate synergistic regenerative and dermatological pathways.

Klow Blend remains a valuable research tool for investigators examining how established peptides interact when combined in defined ratios for skin and tissue regeneration studies.

Why researchers choose Ceritide Research Klow Blend: High-purity, precisely proportioned multi-peptide blend ideal for studying synergistic regenerative and skin research applications.

GHK-Cu

CAS: 49557-75-7
Molecular Formula: C₁₄H₂₄CuN₆O₄
Molecular Weight: 404.9 g/mol
Amino Length: 3 amino acids
Classification: GHK-Cu is classified as a copper-binding tripeptide and belongs to the family of regenerative peptides.
Structure: GHK-Cu is not a linear molecule. Although the peptide backbone (Gly-His-Lys) is linear, the copper ion (Cu²⁺) coordinates with multiple nitrogen atoms in the peptide. This creates chelate rings, forming a stable cyclic coordinated structure around the copper center. The complex typically exhibits square planar geometry.
Sequence: Glicil-Histidil-Lisina
Synonyms: GHK-Cu, Copper Tripeptide-1, Glycyl-L-Histidyl-L-Lysine Copper, GHK Copper Peptide, Copper peptide GHK-Cu, Tripeptide-1 Copper, GHK Copper Complex
NIH PubChem: GHK-Cu (PubChem CID: 133697840)
NIH PubMed Article: GHK-Cu regenerative actions in human skin (Pickart et al., 2018)

BPC-157

CAS:
Molecular Formula: C₆₂H₉₈N₁₆O₂₂
Molecular Weight: 1.419,53 g/mol
Amino Length: 15 amino acids
Classification: BPC-157 is classified as a synthetic stable pentadecapeptide and belongs to the family of cytoprotective research peptides.
Structure: Linear Pentadecapeptide
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Synonyms: BPC-157, Body Protection Compound-157, BPC 157, Stable Gastric Pentadecapeptide BPC 157, PL-14736
PubChem: 137525-51-0
NIH PubMed Article: Stable Gastric Pentadecapeptide BPC 157 and Wound Healing (Seiwerth et al., 2021)

TB-500

CAS: 137525-51-0
Molecular Formula: C₃₈H₆₈N₁₀O₁₄
Molecular Weight: 889.0 g/mol
Amino Length: 7 amino acids
Classification: TB-500 is classified as a synthetic stable heptapeptide and belongs to the family of regenerative research peptides derived from Thymosin Beta-4.
Structure: Linear Heptapeptide
Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Synonyms: TB-500, TB500, TB500 Frag 17-23, Ac-LKKTETQ, N-acetylated LKKTETQ, Thymosin Beta-4 fragment 17-23
NIH PubChem: TB-500 (PubChem CID: 62707662)
NIH PubMed Article: Simultaneous quantification of TB-500 and its metabolites (Rahaman et al., 2024)

KPV

CAS: 67727-97-3
Molecular Formula: C₁₆H₃₀N₄O₄
Molecular Weight: 327,42 g/mol
Amino Length: 3 amino acids
Classification: KPV is classified as a synthetic stable tripeptide and belongs to the family of melanocortin-derived anti-inflammatory research peptides.
Structure: Linear Tripeptide
Sequence: Lys-Pro-Val
Synonyms: KPV tripeptide, Lys-Pro-Val, Lysine-Proline-Valine, α-MSH (11-13), ACTH (11-13), L-Lysyl-L-prolyl-L-valine
NIH PubChem: KPV (PubChem CID: 125672)
NIH PubMed Article: Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease (Kannengiesser et al., 2008)

Storage Guidelines

Peptide Storage Guidelines: Best Practices for Research Stability

At Ceritide Research, we provide high-purity peptides for laboratory and scientific research. Proper storage preserves peptide integrity and supports reliable experimental results.

Storage Guidelines for Lyophilized (Powder) Peptides

Long-Term Storage: Keep at -20°C (-4°F) or lower (ideally -80°C / -112°F) for multi-year stability.
Short-Term Storage: Refrigerate at 2–8°C (36–46°F) for weeks to a few months. Minimize room temperature exposure.
Best Practices: Store in airtight vials with desiccants. Allow vials to reach room temperature in a desiccator before opening. Protect from light and moisture. Aliquot to reduce freeze-thaw cycles.

Storage Guidelines for Reconstituted Peptide Solutions

Once dissolved, peptides are less stable and should be used promptly:

Recommended Temperature: Store at 2–8°C (36–46°F) (refrigerator) for short-term use, typically up to 1–4 weeks depending on the sequence and buffer.
Longer-Term Solution Storage: Aliquot and freeze at -20°C (-4°F) or lower. Avoid storing solutions long-term when possible.
Best Practices: Use sterile techniques, bacteriostatic water or research-grade buffers, and minimize exposure to air and light. Prevent repeated freeze-thaw cycles.

For Research Use Only
All products from Ceritide Research are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Our peptides are intended exclusively for in vitro scientific research and are not for human or veterinary use.

Frequently Asked Questions

What peptides are included in KLOW and at what dosages?

KLOW contains:

GHK-Cu – 50 mg (62.5%)
BPC-157 – 10 mg (12.5%)
TB-500 – 10 mg (12.5%)
KPV – 10 mg (12.5%)

Total: 80 mg per vial.

What research applications is KLOW commonly studied for?

Researchers commonly use KLOW in experimental models focused on wound healing, tissue regeneration, extracellular matrix remodeling, cell migration, angiogenesis, and inflammation modulation. The blend allows study of potential synergistic interactions between these peptides.

How is KLOW different from GLOW?

While GLOW contains GHK-Cu, BPC-157, and TB-500, KLOW includes an additional peptide, KPV. This makes KLOW particularly useful for research involving inflammatory signaling and epithelial barrier function alongside tissue repair mechanisms.

Can KLOW be studied alongside other research peptides?

Yes. Many researchers explore KLOW in combination with other peptides depending on their experimental design. However, all combinations should be evaluated within proper laboratory protocols and institutional guidelines.

Why does KLOW have a much higher amount of GHK-Cu compared to the other peptides?

The higher proportion of GHK-Cu is intentional. GHK-Cu is included at 50 mg to support research focused on extracellular matrix remodeling and copper-mediated cellular signaling, while the lower amounts of BPC-157, TB-500, and KPV allow researchers to study their complementary effects in a balanced ratio.

How does KLOW differ from using individual peptides separately?

KLOW allows researchers to study the combined and potentially synergistic effects of GHK-Cu, BPC-157, TB-500, and KPV in a single, consistent formulation. This can simplify experimental design when investigating multi-pathway tissue repair and inflammation models.

What does the blue color of KLOW indicate?

The subtle blue tint in KLOW is due to the copper complex in GHK-Cu. This is a normal and expected characteristic of the blend and does not affect product quality or stability.

Does KLOW contain any fillers or excipients?

No. KLOW is supplied as a pure lyophilized peptide blend with no added fillers or excipients.

KLOW - GHK-Cu + BPC-157 + TB-500 + KPV

$120.00

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Pureza 99%+

Todos los productos se venden únicamente para fines de investigación, laboratorio o análisis, y no son aptos para el consumo humano.