N-acetil Semax amidato

SKU: SEMAX-10

Disponible

$40.00

MG:

10MG

Variante

N-Acetil Semax Amidato es un compuesto de investigación heptapéptido sintético derivado de un fragmento de la hormona adrenocorticotrófica (ACTH) y modificado con acetilación N-terminal y amidación C-terminal para mejorar la estabilidad molecular y la resistencia a la degradación enzimática. Caracterizado por su secuencia lineal de aminoácidos definida, bajo peso molecular y propiedades fisicoquímicas bien documentadas, el N-Acetil Semax Amidato es ampliamente referenciado en el análisis de la estructura-función de neuropéptidos, estudios de interacción con receptores e investigación de señalización bioquímica. Estas modificaciones químicas preservan la identidad molecular establecida del péptido al tiempo que mejoran la consistencia para la investigación analítica.

Product Specifications

Size: 10MG
Form: Lyophilized Powder
Appearance: White to off-white powder
Weight: 0.2 lb
Dimensions: 2" x 2" x 2"

COA's & Testing

Chemical Purity: >99%
Purity & Identification Testing: HPLC & Mass Spectrometry
Net Content Weight Testing: Milligram Weight
Endotoxin Testing: < 0% Bacterial Endotoxins

Regulatory & Intended Use

Regulatory Status: Solo para uso en investigación (RUO)
Chemical Grade: Laboratory, Research y Analytical

Research-Use Attestation

I confirm I am 21+ years of age or older.

I certify the information provided is true and accurate. I confirm this purchase is for laboratory research use only (not for human or animal consumption). I acknowledge the company may use IP address and other reasonable verification methods to authenticate the information provided.

Scientific Background

Discovery and Development
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). It was developed in Russia during the 1980s and 1990s by researchers at the Institute of Molecular Genetics of the Russian Academy of Sciences. The N-Acetyl Semax Amidate version was later created by adding N-terminal acetylation and C-terminal amidation. These modifications significantly improve metabolic stability, resistance to enzymatic breakdown, and overall bioavailability, making it more suitable for laboratory research applications while maintaining the core biological activity of the parent peptide.

Key Milestones in Research

1980s–1990s: Development and initial characterization of Semax as a neuroprotective and nootropic peptide in Russia.
2000s: Introduction of the N-Acetyl and Amidate forms to enhance stability and duration of action for research use.
2010s–Present: Extensive laboratory studies exploring its effects on cognitive enhancement, neuroprotection, neuroplasticity, BDNF expression, and recovery from neurological stress in experimental models.

N-Acetyl Semax Amidate remains a valuable research tool for investigators studying neuropeptide signaling, cognitive function, neuroprotection, and stress adaptation pathways.

Why researchers choose Ceritide Research N-Acetyl Semax Amidate: High-purity stabilized heptapeptide with verified ≥99% purity by independent HPLC and mass spectrometry. Supplied in sterile vials ready for laboratory use.

N-Acetyl Semax Amidate

CAS: 2920938-90-3
Molecular Formula: C₃₉H₅₄N₁₀O₁₀S
Molecular Weight: 855.0 g/mol (or 854.97 g/mol)
Amino Length: 7 aminoácidos
Classification: Synthetic heptapeptide analog of ACTH(4-10); N-acetylated and C-terminally amidated nootropic/neuroprotective research peptide for enhanced stability.
Structure: Linear heptapeptide with N-terminal acetylation and C-terminal amidation: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂.
Sequence: MEHFPGP (core; full modified: Ac-MEHFPGP-NH₂).
Synonyms: N-Acetyl Semax Amidate, N-Acetyl Semax, Ac-MEHFPGP-NH₂, modified Semax, ACTH(4-10) analog.
NIH PubChem: N-acetyl semax amidate (CID 172638603)
NIH PubMed Article:

Storage Guidelines

Peptide Storage Guidelines: Best Practices for Research Stability

At Ceritide Research, we provide high-purity peptides for laboratory and scientific research. Proper storage preserves peptide integrity and supports reliable experimental results.

Storage Guidelines for Lyophilized (Powder) Peptides

Long-Term Storage: Keep at -20°C (-4°F) or lower (ideally -80°C / -112°F) for multi-year stability.
Short-Term Storage: Refrigerate at 2–8°C (36–46°F) for weeks to a few months. Minimize room temperature exposure.
Best Practices: Store in airtight vials with desiccants. Allow vials to reach room temperature in a desiccator before opening. Protect from light and moisture. Aliquot to reduce freeze-thaw cycles.

Storage Guidelines for Reconstituted Peptide Solutions

Once dissolved, peptides are less stable and should be used promptly:

Recommended Temperature: Store at 2–8°C (36–46°F) (refrigerator) for short-term use, typically up to 1–4 weeks depending on the sequence and buffer.
Longer-Term Solution Storage: Aliquot and freeze at -20°C (-4°F) or lower. Avoid storing solutions long-term when possible.
Best Practices: Use sterile techniques, bacteriostatic water or research-grade buffers, and minimize exposure to air and light. Prevent repeated freeze-thaw cycles.

For Research Use Only
All products from Ceritide Research are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Our peptides are intended exclusively for in vitro scientific research and are not for human or veterinary use.

Frequently Asked Questions

What is N-Acetyl Semax Amidate?

N-Acetyl Semax Amidate is a high-purity stabilized heptapeptide research compound from Ceritide Research. It is the acetylated and amidated version of Semax, designed for laboratory studies on cognitive enhancement, neuroprotection, neuroplasticity, and memory function.

What are the primary research applications of N-Acetyl Semax Amidate?

Researchers use N-Acetyl Semax Amidate for nootropic research, cognitive enhancement studies, neuroprotection models, memory and learning investigations, BDNF expression analysis, and recovery from neurological stress in controlled lab settings.

What are the benefits of the N-Acetyl and Amidate modifications in Semax?

The N-Acetyl and C-terminal Amidate modifications significantly enhance metabolic stability and resistance to enzymatic degradation, providing longer-lasting and more consistent results in laboratory experiments.

Is N-Acetyl Semax Amidate the same as regular Semax?

No. N-Acetyl Semax Amidate is a chemically enhanced version with improved stability, making it the preferred choice for researchers conducting extended or repeated dosing studies.

Can N-Acetyl Semax Amidate be combined with other research peptides?

Yes. It is commonly studied alongside N-Acetyl Selank Amidate, DSIP, VIP, and other neuroprotective or nootropic research peptides to explore synergistic effects.

N-acetil Semax amidato

$40.00

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Pureza 99%+

Todos los productos se venden únicamente para fines de investigación, laboratorio o análisis, y no son aptos para el consumo humano.