N-Acetil Selank Amidato

SKU: SLANK-10

Disponible

$40.00

MG:

10MG

Variante

N-Acetil Selank Amidato es un compuesto de investigación heptapéptido sintético derivado del péptido inmunomodulador natural tuftsina y modificado con acetilación N-terminal y amidación C-terminal para mejorar la estabilidad molecular y la resistencia a la degradación enzimática. Caracterizado por su secuencia de aminoácidos definida y propiedades fisicoquímicas documentadas, el N-Acetil Selank Amidato es ampliamente referenciado en el análisis de la estructura-función de neuropéptidos, estudios de interacción con receptores e investigación de señalización bioquímica. Estas modificaciones estructurales lo distinguen de los análogos no acetilados, preservando al mismo tiempo su identidad molecular establecida para uso en investigación analítica.

Product Specifications

Size: 10MG
Form: Lyophilized Powder
Appearance: White to off-white powder
Weight: 0.2 lb
Dimensions: 2" x 2" x 2"

COA's & Testing

Chemical Purity: >99%
Purity & Identification Testing: HPLC & Mass Spectrometry
Net Content Weight Testing: Milligram Weight
Endotoxin Testing: < 0% Bacterial Endotoxins

Regulatory & Intended Use

Regulatory Status: Solo para uso en investigación (RUO)
Chemical Grade: Laboratory, Research y Analytical

Research-Use Attestation

I confirm I am 21+ years of age or older.

I certify the information provided is true and accurate. I confirm this purchase is for laboratory research use only (not for human or animal consumption). I acknowledge the company may use IP address and other reasonable verification methods to authenticate the information provided.

Scientific Background

Discovery and Development
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed in Russia in the late 1980s and 1990s by researchers at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is an analog of the naturally occurring immunomodulatory peptide tuftsin. To improve metabolic stability and resistance to enzymatic degradation, researchers created the N-Acetyl Selank Amidate version by adding N-terminal acetylation and C-terminal amidation. These chemical modifications enhance bioavailability and shelf-life while preserving the core pharmacological profile, making it more suitable for laboratory research.

Key Milestones in Research

1980s–1990s: Development and initial characterization of Selank as an anxiolytic and immunomodulatory peptide in Russia.
2000s: Introduction of acetylated and amidated versions (N-Acetyl Selank Amidate) to improve stability for research applications.
2010s–Present: Expanded laboratory studies on its effects on anxiety, cognitive function, neuroprotection, and immune modulation. It is frequently used in models investigating neuropeptide signaling, stress response, and nootropic pathways.

N-Acetyl Selank Amidate remains a valuable research tool for investigators studying neuropeptide-based modulation of behavior, stress, and immune function in controlled experimental settings.

Why researchers choose Ceritide Research N-Acetyl Selank Amidate: High-purity stabilized heptapeptide with verified ≥99% purity, ideal for nootropic, anxiolytic, and neuroprotective research.

N-Acetyl Selank Amidate

CAS: 129954-34-3
Molecular Formula: C₃₅H₅₉N₁₁O₁₀
Molecular Weight: 793.9 g/mol
Amino Length: 7 Aminoácidos
Classification: Synthetic heptapeptide analog of tuftsin; modified nootropic/anxiolytic research peptide (N-acetylated and C-terminally amidated for enhanced stability).
Structure: Linear heptapeptide with N-terminal acetylation and C-terminal amidation: Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂.
Sequence: TKPRPGPTKPRPGP (core; full modified: Ac-TKPRPGP-NH₂).
Synonyms: N-Acetyl Selank Amidate, N-Acetyl Selank, Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂, modified Selank, tuftsin analog.
NIH PubChem: N-Acetyl Selank (PubChem CID: 133082488)
NIH PubMed Article: Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission – Volkova et al., 2016

Storage Guidelines

Peptide Storage Guidelines: Best Practices for Research Stability

At Ceritide Research, we provide high-purity peptides for laboratory and scientific research. Proper storage preserves peptide integrity and supports reliable experimental results.

Storage Guidelines for Lyophilized (Powder) Peptides

Long-Term Storage: Keep at -20°C (-4°F) or lower (ideally -80°C / -112°F) for multi-year stability.
Short-Term Storage: Refrigerate at 2–8°C (36–46°F) for weeks to a few months. Minimize room temperature exposure.
Best Practices: Store in airtight vials with desiccants. Allow vials to reach room temperature in a desiccator before opening. Protect from light and moisture. Aliquot to reduce freeze-thaw cycles.

Storage Guidelines for Reconstituted Peptide Solutions

Once dissolved, peptides are less stable and should be used promptly:

Recommended Temperature: Store at 2–8°C (36–46°F) (refrigerator) for short-term use, typically up to 1–4 weeks depending on the sequence and buffer.
Longer-Term Solution Storage: Aliquot and freeze at -20°C (-4°F) or lower. Avoid storing solutions long-term when possible.
Best Practices: Use sterile techniques, bacteriostatic water or research-grade buffers, and minimize exposure to air and light. Prevent repeated freeze-thaw cycles.

For Research Use Only
All products from Ceritide Research are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Our peptides are intended exclusively for in vitro scientific research and are not for human or veterinary use.

Frequently Asked Questions

What is N-Acetyl Selank Amidate?

N-Acetyl Selank Amidate is a high-purity stabilized heptapeptide research compound from Ceritide Research. It is the acetylated and amidated version of Selank, designed for laboratory studies on anxiety, stress adaptation, immunomodulation, and cognitive function.

What are the main research applications of N-Acetyl Selank Amidate?

Researchers use N-Acetyl Selank Amidate for anxiolytic studies, stress response research, cognitive enhancement models, neuroprotection, immunomodulatory pathway investigations, and overall brain health experiments.

What are the benefits of the N-Acetyl and Amidate modifications?

The N-Acetyl and C-terminal Amidate modifications significantly improve metabolic stability and resistance to enzymatic breakdown, allowing for more consistent and longer-lasting results in research settings.

Is N-Acetyl Selank Amidate the same as regular Selank?

No. N-Acetyl Selank Amidate is a chemically modified version with enhanced stability, making it preferred by researchers for extended or repeated dosing studies compared to non-acetylated Selank.

Can N-Acetyl Selank Amidate be used with other research peptides?

Yes. It is frequently studied in combination with N-Acetyl Semax Amidate, DSIP, VIP, and other nootropic or neuroprotective research peptides for synergistic effect studies.

N-Acetil Selank Amidato

$40.00

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Pureza 99%+

Todos los productos se venden únicamente para fines de investigación, laboratorio o análisis, y no son aptos para el consumo humano.