N-Acetyl Semax Amidate

SKU: SEMAX-10

In stock

$40.00

MG:

10MG

Variant

N‑Acetyl Semax Amidate is a synthetic heptapeptide research compound derived from a fragment of adrenocorticotropic hormone (ACTH) and modified with N‑terminal acetylation and C‑terminal amidation to enhance molecular stability and resistance to enzymatic degradation. Characterized by its defined linear amino‑acid sequence, low molecular weight, and well‑documented physicochemical properties, N‑Acetyl Semax Amidate is widely referenced in neuropeptide structure–function analysis, receptor interaction studies, and biochemical signaling research. These chemical modifications preserve the peptide’s established molecular identity while improving consistency for analytical investigation.

Ceritide Research offers N-Acetyl Semax Amidate as a premium 10mg lyophilized research peptide with verified ≥99% purity confirmed by independent HPLC and mass spectrometry. Supplied in a sterile vial and ready for immediate reconstitution per your protocol, this product delivers the reliability top research labs demand.

The Purest Peptides. Period.

Research Use Only. Not for human or veterinary use.

Product Specifications

Size: 10MG
Form: Lyophilized Powder
Appearance: White to off-white powder
Weight: 0.2 lb
Dimensions: 2" x 2" x 2"

COA's & Testing

Chemical Purity: >99%
Purity & Identification Testing: HPLC & Mass Spectrometry
Net Content Weight Testing: Milligram Weight
Endotoxin Testing: < 0% Bacterial Endotoxins

Regulatory & Intended Use

Regulatory Status: Research Use Only (RUO)
Chemical Grade: Laboratory, Research, and Analytical

Research-Use Attestation

I confirm I am 21+ years of age or older.

I certify the information provided is true and accurate. I confirm this purchase is for laboratory research use only (not for human or animal consumption). I acknowledge the company may use IP address and other reasonable verification methods to authenticate the information provided.

Scientific Background

Discovery and Development
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). It was developed in Russia during the 1980s and 1990s by researchers at the Institute of Molecular Genetics of the Russian Academy of Sciences. The N-Acetyl Semax Amidate version was later created by adding N-terminal acetylation and C-terminal amidation. These modifications significantly improve metabolic stability, resistance to enzymatic breakdown, and overall bioavailability, making it more suitable for laboratory research applications while maintaining the core biological activity of the parent peptide.

Key Milestones in Research

1980s–1990s: Development and initial characterization of Semax as a neuroprotective and nootropic peptide in Russia.
2000s: Introduction of the N-Acetyl and Amidate forms to enhance stability and duration of action for research use.
2010s–Present: Extensive laboratory studies exploring its effects on cognitive enhancement, neuroprotection, neuroplasticity, BDNF expression, and recovery from neurological stress in experimental models.

N-Acetyl Semax Amidate remains a valuable research tool for investigators studying neuropeptide signaling, cognitive function, neuroprotection, and stress adaptation pathways.

Why researchers choose Ceritide Research N-Acetyl Semax Amidate: High-purity stabilized heptapeptide with verified ≥99% purity by independent HPLC and mass spectrometry. Supplied in sterile vials ready for laboratory use.

N-Acetyl Semax Amidate

CAS: 2920938-90-3
Molecular Formula: C₃₉H₅₄N₁₀O₁₀S
Molecular Weight: 855.0 g/mol (or 854.97 g/mol)
Amino Length: 7 Amino Acids
Classification: Synthetic heptapeptide analog of ACTH(4-10); N-acetylated and C-terminally amidated nootropic/neuroprotective research peptide for enhanced stability.
Structure: Linear heptapeptide with N-terminal acetylation and C-terminal amidation: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂.
Sequence: MEHFPGP (core; full modified: Ac-MEHFPGP-NH₂).
Synonyms: N-Acetyl Semax Amidate, N-Acetyl Semax, Ac-MEHFPGP-NH₂, modified Semax, ACTH(4-10) analog.
NIH PubChem: N-acetyl semax amidate (CID 172638603)
NIH PubMed Article:

Storage Guidelines

Peptide Storage Guidelines: Best Practices for Research Stability

At Ceritide Research, we provide high-purity peptides for laboratory and scientific research. Proper storage preserves peptide integrity and supports reliable experimental results.

Storage Guidelines for Lyophilized (Powder) Peptides

Long-Term Storage: Keep at -20°C (-4°F) or lower (ideally -80°C / -112°F) for multi-year stability.
Short-Term Storage: Refrigerate at 2–8°C (36–46°F) for weeks to a few months. Minimize room temperature exposure.
Best Practices: Store in airtight vials with desiccants. Allow vials to reach room temperature in a desiccator before opening. Protect from light and moisture. Aliquot to reduce freeze-thaw cycles.

Storage Guidelines for Reconstituted Peptide Solutions

Once dissolved, peptides are less stable and should be used promptly:

Recommended Temperature: Store at 2–8°C (36–46°F) (refrigerator) for short-term use, typically up to 1–4 weeks depending on the sequence and buffer.
Longer-Term Solution Storage: Aliquot and freeze at -20°C (-4°F) or lower. Avoid storing solutions long-term when possible.
Best Practices: Use sterile techniques, bacteriostatic water or research-grade buffers, and minimize exposure to air and light. Prevent repeated freeze-thaw cycles.

For Research Use Only
All products from Ceritide Research are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Our peptides are intended exclusively for in vitro scientific research and are not for human or veterinary use.

Frequently Asked Questions

What is N-Acetyl Semax Amidate?

N-Acetyl Semax Amidate is a high-purity stabilized heptapeptide research compound from Ceritide Research. It is the acetylated and amidated version of Semax, designed for laboratory studies on cognitive enhancement, neuroprotection, neuroplasticity, and memory function.

What are the primary research applications of N-Acetyl Semax Amidate?

Researchers use N-Acetyl Semax Amidate for nootropic research, cognitive enhancement studies, neuroprotection models, memory and learning investigations, BDNF expression analysis, and recovery from neurological stress in controlled lab settings.

What are the benefits of the N-Acetyl and Amidate modifications in Semax?

The N-Acetyl and C-terminal Amidate modifications significantly enhance metabolic stability and resistance to enzymatic degradation, providing longer-lasting and more consistent results in laboratory experiments.

Is N-Acetyl Semax Amidate the same as regular Semax?

No. N-Acetyl Semax Amidate is a chemically enhanced version with improved stability, making it the preferred choice for researchers conducting extended or repeated dosing studies.

Can N-Acetyl Semax Amidate be combined with other research peptides?

Yes. It is commonly studied alongside N-Acetyl Selank Amidate, DSIP, VIP, and other neuroprotective or nootropic research peptides to explore synergistic effects.

N-Acetyl Semax Amidate

$40.00

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Purity 99%+

All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.